Viruses, Vol. 16, Pages 784: Mpox (Monkeypox) Virus and Its Co-Infection with HIV, Sexually Transmitted Infections, or Bacterial Superinfections: Double Whammy or a New Prime Culprit?
krinsky
Epidemiologic studies have established that mpox (formerly known as monkeypox) outbreaks worldwide in 2022–2023, due to Clade IIb mpox virus (MPXV), disproportionately affected gay, bisexual, and other men who have sex with men. More than 35% and 40% of the mpox cases suffer from co-infection with HIV and sexually transmitted infections (STIs) (e.g., Chlamydia trachomatis, Neisseria gonorrhoeae, Treponema pallidum, and herpes simplex virus), respectively. Bacterial superinfection can also occur. Co-infection of MPXV and other infectious agents may enhance disease severity, deteriorate outcomes, el...
Source: Viruses - May 15, 2024 Category: Virology Authors: Benjamin M. Liu Natella Y. Rakhmanina Zhilong Yang Michael I. Bukrinsky Tags: Perspective Source Type: research
Genomic Analysis of Monkeypox Virus During the 2023 Epidemic in Korea
J Korean Med Sci. 2024 May 13;39(18):e165. doi: 10.3346/jkms.2024.39.e165.ABSTRACTWe aimed to characterize the genomes of monkeypox virus isolates from the Far East, providing insights into viral transmission and evolution. Genomic analysis was conducted on 8 isolates obtained from patients with monkeypox virus disease in the Republic of Korea between May 2022 and early 2023. These isolates were classified into Clade IIb. Distinct lineages, including B.1.1, A.2.1, and B.1.3, were observed in 2022 and 2023 isolates, with only the B.1.3 lineage detected in six isolates of 2023. These genetic features were specific to Far Eas...
Source: Journal of Korean Medical Science - May 14, 2024 Category: Biomedical Science Authors: Chi-Hwan Choi Minji Lee Sang Eun Lee Jin-Won Kim Hwachul Shin Myung-Min Choi Hwajung Yi Min-Kyung Kim Jaehyun Jeon Jun-Sun Park Yeonjae Kim So Yun Lim BumSik Chin Yoon-Seok Chung Source Type: research
Genomic Analysis of Monkeypox Virus During the 2023 Epidemic in Korea
J Korean Med Sci. 2024 May 13;39(18):e165. doi: 10.3346/jkms.2024.39.e165.ABSTRACTWe aimed to characterize the genomes of monkeypox virus isolates from the Far East, providing insights into viral transmission and evolution. Genomic analysis was conducted on 8 isolates obtained from patients with monkeypox virus disease in the Republic of Korea between May 2022 and early 2023. These isolates were classified into Clade IIb. Distinct lineages, including B.1.1, A.2.1, and B.1.3, were observed in 2022 and 2023 isolates, with only the B.1.3 lineage detected in six isolates of 2023. These genetic features were specific to Far Eas...
Source: J Korean Med Sci - May 14, 2024 Category: General Medicine Authors: Chi-Hwan Choi Minji Lee Sang Eun Lee Jin-Won Kim Hwachul Shin Myung-Min Choi Hwajung Yi Min-Kyung Kim Jaehyun Jeon Jun-Sun Park Yeonjae Kim So Yun Lim BumSik Chin Yoon-Seok Chung Source Type: research
Adapting an artificial intelligence sexually transmitted diseases symptom checker tool for Mpox detection: the HeHealth experience
Sex Health. 2024 May;21:SH23197. doi: 10.1071/SH23197.ABSTRACTArtificial Intelligence (AI) applications have shown promise in the management of pandemics. In response to the global Monkeypox (Mpox) outbreak, the HeHealth.ai team leveraged an existing tool to screen for sexually transmitted diseases (STD) to develop a digital screening test for symptomatic Mpox using AI. Before the global Mpox outbreak, the team developed a smartphone app (HeHealth) where app users can use a smartphone to photograph their own penises to screen for symptomatic STD. The AI model initially used 5000 cases and a modified convolutional neural ne...
Source: Herpes - May 14, 2024 Category: Infectious Diseases Authors: Rayner Kay Jin Tan Dilruk Perera Salomi Arasaratnam Yudara Kularathne Source Type: research
Genomic Analysis of Monkeypox Virus During the 2023 Epidemic in Korea
J Korean Med Sci. 2024 May 13;39(18):e165. doi: 10.3346/jkms.2024.39.e165.ABSTRACTWe aimed to characterize the genomes of monkeypox virus isolates from the Far East, providing insights into viral transmission and evolution. Genomic analysis was conducted on 8 isolates obtained from patients with monkeypox virus disease in the Republic of Korea between May 2022 and early 2023. These isolates were classified into Clade IIb. Distinct lineages, including B.1.1, A.2.1, and B.1.3, were observed in 2022 and 2023 isolates, with only the B.1.3 lineage detected in six isolates of 2023. These genetic features were specific to Far Eas...
Source: Journal of Korean Medical Science - May 14, 2024 Category: Biomedical Science Authors: Chi-Hwan Choi Minji Lee Sang Eun Lee Jin-Won Kim Hwachul Shin Myung-Min Choi Hwajung Yi Min-Kyung Kim Jaehyun Jeon Jun-Sun Park Yeonjae Kim So Yun Lim BumSik Chin Yoon-Seok Chung Source Type: research
Genomic Analysis of Monkeypox Virus During the 2023 Epidemic in Korea
J Korean Med Sci. 2024 May 13;39(18):e165. doi: 10.3346/jkms.2024.39.e165.ABSTRACTWe aimed to characterize the genomes of monkeypox virus isolates from the Far East, providing insights into viral transmission and evolution. Genomic analysis was conducted on 8 isolates obtained from patients with monkeypox virus disease in the Republic of Korea between May 2022 and early 2023. These isolates were classified into Clade IIb. Distinct lineages, including B.1.1, A.2.1, and B.1.3, were observed in 2022 and 2023 isolates, with only the B.1.3 lineage detected in six isolates of 2023. These genetic features were specific to Far Eas...
Source: J Korean Med Sci - May 14, 2024 Category: General Medicine Authors: Chi-Hwan Choi Minji Lee Sang Eun Lee Jin-Won Kim Hwachul Shin Myung-Min Choi Hwajung Yi Min-Kyung Kim Jaehyun Jeon Jun-Sun Park Yeonjae Kim So Yun Lim BumSik Chin Yoon-Seok Chung Source Type: research
Genomic Analysis of Monkeypox Virus During the 2023 Epidemic in Korea
J Korean Med Sci. 2024 May 13;39(18):e165. doi: 10.3346/jkms.2024.39.e165.ABSTRACTWe aimed to characterize the genomes of monkeypox virus isolates from the Far East, providing insights into viral transmission and evolution. Genomic analysis was conducted on 8 isolates obtained from patients with monkeypox virus disease in the Republic of Korea between May 2022 and early 2023. These isolates were classified into Clade IIb. Distinct lineages, including B.1.1, A.2.1, and B.1.3, were observed in 2022 and 2023 isolates, with only the B.1.3 lineage detected in six isolates of 2023. These genetic features were specific to Far Eas...
Source: Journal of Korean Medical Science - May 14, 2024 Category: Biomedical Science Authors: Chi-Hwan Choi Minji Lee Sang Eun Lee Jin-Won Kim Hwachul Shin Myung-Min Choi Hwajung Yi Min-Kyung Kim Jaehyun Jeon Jun-Sun Park Yeonjae Kim So Yun Lim BumSik Chin Yoon-Seok Chung Source Type: research
Genomic Analysis of Monkeypox Virus During the 2023 Epidemic in Korea
J Korean Med Sci. 2024 May 13;39(18):e165. doi: 10.3346/jkms.2024.39.e165.ABSTRACTWe aimed to characterize the genomes of monkeypox virus isolates from the Far East, providing insights into viral transmission and evolution. Genomic analysis was conducted on 8 isolates obtained from patients with monkeypox virus disease in the Republic of Korea between May 2022 and early 2023. These isolates were classified into Clade IIb. Distinct lineages, including B.1.1, A.2.1, and B.1.3, were observed in 2022 and 2023 isolates, with only the B.1.3 lineage detected in six isolates of 2023. These genetic features were specific to Far Eas...
Source: J Korean Med Sci - May 14, 2024 Category: General Medicine Authors: Chi-Hwan Choi Minji Lee Sang Eun Lee Jin-Won Kim Hwachul Shin Myung-Min Choi Hwajung Yi Min-Kyung Kim Jaehyun Jeon Jun-Sun Park Yeonjae Kim So Yun Lim BumSik Chin Yoon-Seok Chung Source Type: research
Genomic Analysis of Monkeypox Virus During the 2023 Epidemic in Korea
J Korean Med Sci. 2024 May 13;39(18):e165. doi: 10.3346/jkms.2024.39.e165.ABSTRACTWe aimed to characterize the genomes of monkeypox virus isolates from the Far East, providing insights into viral transmission and evolution. Genomic analysis was conducted on 8 isolates obtained from patients with monkeypox virus disease in the Republic of Korea between May 2022 and early 2023. These isolates were classified into Clade IIb. Distinct lineages, including B.1.1, A.2.1, and B.1.3, were observed in 2022 and 2023 isolates, with only the B.1.3 lineage detected in six isolates of 2023. These genetic features were specific to Far Eas...
Source: Journal of Korean Medical Science - May 14, 2024 Category: Biomedical Science Authors: Chi-Hwan Choi Minji Lee Sang Eun Lee Jin-Won Kim Hwachul Shin Myung-Min Choi Hwajung Yi Min-Kyung Kim Jaehyun Jeon Jun-Sun Park Yeonjae Kim So Yun Lim BumSik Chin Yoon-Seok Chung Source Type: research
Genomic Analysis of Monkeypox Virus During the 2023 Epidemic in Korea
J Korean Med Sci. 2024 May 13;39(18):e165. doi: 10.3346/jkms.2024.39.e165.ABSTRACTWe aimed to characterize the genomes of monkeypox virus isolates from the Far East, providing insights into viral transmission and evolution. Genomic analysis was conducted on 8 isolates obtained from patients with monkeypox virus disease in the Republic of Korea between May 2022 and early 2023. These isolates were classified into Clade IIb. Distinct lineages, including B.1.1, A.2.1, and B.1.3, were observed in 2022 and 2023 isolates, with only the B.1.3 lineage detected in six isolates of 2023. These genetic features were specific to Far Eas...
Source: J Korean Med Sci - May 14, 2024 Category: General Medicine Authors: Chi-Hwan Choi Minji Lee Sang Eun Lee Jin-Won Kim Hwachul Shin Myung-Min Choi Hwajung Yi Min-Kyung Kim Jaehyun Jeon Jun-Sun Park Yeonjae Kim So Yun Lim BumSik Chin Yoon-Seok Chung Source Type: research
Genomic Analysis of Monkeypox Virus During the 2023 Epidemic in Korea
J Korean Med Sci. 2024 May 13;39(18):e165. doi: 10.3346/jkms.2024.39.e165.ABSTRACTWe aimed to characterize the genomes of monkeypox virus isolates from the Far East, providing insights into viral transmission and evolution. Genomic analysis was conducted on 8 isolates obtained from patients with monkeypox virus disease in the Republic of Korea between May 2022 and early 2023. These isolates were classified into Clade IIb. Distinct lineages, including B.1.1, A.2.1, and B.1.3, were observed in 2022 and 2023 isolates, with only the B.1.3 lineage detected in six isolates of 2023. These genetic features were specific to Far Eas...
Source: Journal of Korean Medical Science - May 14, 2024 Category: Biomedical Science Authors: Chi-Hwan Choi Minji Lee Sang Eun Lee Jin-Won Kim Hwachul Shin Myung-Min Choi Hwajung Yi Min-Kyung Kim Jaehyun Jeon Jun-Sun Park Yeonjae Kim So Yun Lim BumSik Chin Yoon-Seok Chung Source Type: research
Genomic Analysis of Monkeypox Virus During the 2023 Epidemic in Korea
J Korean Med Sci. 2024 May 13;39(18):e165. doi: 10.3346/jkms.2024.39.e165.ABSTRACTWe aimed to characterize the genomes of monkeypox virus isolates from the Far East, providing insights into viral transmission and evolution. Genomic analysis was conducted on 8 isolates obtained from patients with monkeypox virus disease in the Republic of Korea between May 2022 and early 2023. These isolates were classified into Clade IIb. Distinct lineages, including B.1.1, A.2.1, and B.1.3, were observed in 2022 and 2023 isolates, with only the B.1.3 lineage detected in six isolates of 2023. These genetic features were specific to Far Eas...
Source: J Korean Med Sci - May 14, 2024 Category: General Medicine Authors: Chi-Hwan Choi Minji Lee Sang Eun Lee Jin-Won Kim Hwachul Shin Myung-Min Choi Hwajung Yi Min-Kyung Kim Jaehyun Jeon Jun-Sun Park Yeonjae Kim So Yun Lim BumSik Chin Yoon-Seok Chung Source Type: research
Genomic Analysis of Monkeypox Virus During the 2023 Epidemic in Korea
J Korean Med Sci. 2024 May 13;39(18):e165. doi: 10.3346/jkms.2024.39.e165.ABSTRACTWe aimed to characterize the genomes of monkeypox virus isolates from the Far East, providing insights into viral transmission and evolution. Genomic analysis was conducted on 8 isolates obtained from patients with monkeypox virus disease in the Republic of Korea between May 2022 and early 2023. These isolates were classified into Clade IIb. Distinct lineages, including B.1.1, A.2.1, and B.1.3, were observed in 2022 and 2023 isolates, with only the B.1.3 lineage detected in six isolates of 2023. These genetic features were specific to Far Eas...
Source: Journal of Korean Medical Science - May 14, 2024 Category: Biomedical Science Authors: Chi-Hwan Choi Minji Lee Sang Eun Lee Jin-Won Kim Hwachul Shin Myung-Min Choi Hwajung Yi Min-Kyung Kim Jaehyun Jeon Jun-Sun Park Yeonjae Kim So Yun Lim BumSik Chin Yoon-Seok Chung Source Type: research
Adapting an artificial intelligence sexually transmitted diseases symptom checker tool for Mpox detection: the HeHealth experience
Rayner Kay Jin Tan, Dilruk Perera, Salomi Arasaratnam, Yudara Kularathne - Volume 21(3) Prior to the global Monkeypox (Mpox) outbreak, we developed a smartphone app (HeHealth) where users can take pictures of their penises with a smartphone to screen for symptomatic sexually transmitted diseases. We further developed the Mpox tool that involved formative research, stakeholder engagement, rapid consolidation of Mpox images, a validation study, and implementation. Artificial intelligence and machine learning approaches can be initiated by smaller datasets and refined along the way, which is important in the event of global p...
Source: Sexual Health - May 14, 2024 Category: Sexual Medicine Authors: Rayner Kay Jin Tan Dilruk Perera Salomi Arasaratnam Yudara Kularathne Source Type: research
An atypical presentation of human monkeypox infection with clinicopathologic correlation
We describe atypical cutaneous manifestations involving widespread erythematous pustules with preceding anogenital ulcerations and concomitant bilateral inguinal lymphadenopathy. Clinicopathologic correlation is used to assist in the workup and establishing the diagnosis. Our case supports others reported in the literature that suggest sexual contact as a means of transmission. More research is needed that investigates the presence of infection in both men and women, including those who could act as carriers, to elucidate other pathways in this evolving yet evasive viral disease. (Source: Dermatology Online Journal)
Source: Dermatology Online Journal - May 10, 2024 Category: Dermatology Authors: Colon, Jessica Source Type: research
